Performed grants and research projects

Performed grants:

AZV NV 19-07-00210 "Primary ciliary dyskinesia: Genetic, structural and functional determinants of the desease course and prognosis. Principal investigator prof. MUDr. P. Pohunek, CSc., co-investigators: MUDr. J. Uhlík, Ph.D., MUDr. A. Felšöová, MUDr. S. Kadlecová, MUDr. V. Martinů, 2019-2022

GAUK 907019 "Use of hydrogel carrier of chemotherapeutics for retinoblastoma treatment." Principal investigator MUDr. M. Kodetová, tutor doc. MUDr. P. Pochop, Ph.D., co-investigator MUDr. J. Uhlík, Ph.D., 2019-2021.

GAUK 670119 "Functional, morphological and clinical aspects of ciliary dyskinesia and determinants of prognosis of the patients." Principal investigator MUDr. V. Martinů, tutor prof. MUDr. P. Pohunek, CSc., co-investigators MUDr. J. Uhlík, Ph.D., MUDr. S Kadlecová, 2019-2021.

GAUK 60715 "Correlation between lung function parameters and morphological changes of tracheobronchial tree in children with chronic respiratory disease." Principal investigator MUDr. V. Koucký, tutor prof. MUDr. P. Pohunek, CSc., co-investigators MUDr. L. Hoňková, K. Vráblová, 2015-2017.

GAUK 360213 "Mechanisms and signs of airway remodelling in bronchial asthma and other obstructive respiratory diseases." Principal investigator MUDr. L. Hoňková, tutor prof. MUDr. P. Pohunek, CSc., co-investigators MUDr. J. Uhlík, Ph.D., MUDr. K. Beránková, MUDr. J. Djakow, 2013-2015. 

IP 336057 "Standardized evaluation of the knowledge level in students." Principal co-ordinator doc. MVDr. L. Vajner, CSc., co-workers MUDr. J. Uhlík, Ph.D., doc. RNDr. J. Mareš, CSc., MUDr. J. Feberová, Ph.D., 2014.

GAUK 1262414 "Príprava nanovlákenného PVA nosiča pre osteogénnu regeneráciu s kontrolovaným rozpadom using matrix-metalloproteinases." Principal investigator RNDr. Martin Kráľovič, tutor prof. RNDr. Evžen Amler, CSc., co-worker doc. MVDr. L. Vajner, CSc., 2014-2016.

GAUK 340911 "Early signs of bronchial asthma in children. Morphological and functional onset of disease." Principal investigator MUDr. K. Beránková, tutor prof. MUDr. P. Pohunek, CSc., co-investigators MUDr. J. Uhlík, Ph.D., MUDr. L. Hoňková, 2011-2013.

FRVŠ 215 A/2011 „Establishing the new laboratory for taking light microscopy- and fluorescence-images of cells and tissues suitable for interactive atlases.“ Principal co-ordinator doc. MVDr. L. Vajner, CSc., co-workers MUDr. J. Uhlík, Ph.D., MUDr. Tomáš Novotný, Roman Wasserbauer, Jiří Soukup, Martin Wasserbauer, Jakub Krejčí, Vojtěch Švehlík, 2011.

GAČR P303/11/0298 "Biochemical and morphologic aspects of the early postnatal development of the brain and heart. The role of free radicals." Principal investigator prof. RNDr. J. Wilhelm, Ph.D., co-workers doc. MVDr. L. Vajner, CSc., MUDr. J. Uhlík, Ph.D., 2011-2015.

IGA MZ 11444 „Early symptoms of bronchial asthma in children - functional and morphological consequences of the disease." Principal investigator prof. MUDr. P. Pohunek, CSc., co-investigator MUDr. T. Svobodová, CSc., co-workers MUDr. J. Uhlík, Ph.D., MUDr. K. Urbanová, MUDr. J. Šulc, CSc., 2010-2014.

IGA MZ 11469 „Primary ciliary dyskinesia - new diagnostic and epidemiologic approaches." Principal investigator MUDr. T. Svobodová, CSc., co-investigator MUDr. J. Djakow, co-workers prof. MUDr. P. Pohunek, CSc., MUDr. J. Uhlík, Ph.D., 2010-2014.

IGA MZ 11459 „Immunohistochemical and ultrastructural evaluation of airway wall remodeling in experimentally provoked bronchial asthma." Principal investigator MUDr. J. Uhlík, Ph.D., co-workers doc. MVDr. L. Vajner, CSc., MUDr. K. Urbanová, 2010-2013.

GAČR 202/09/1151 „Two subsequent focused shock waves and their potential use in tumour therapy and controlled release of drugs.“ Principal investigator Ing. Petr Lukeš, Ph.D., co-investigators prof. MUDr. RNDr. Jiří Beneš, CSc.a doc. RNDr. Hana Kolářová, CSc., co-worker doc. MVDr. Luděk Vajner, CSc., 2009-2011.
MŠMT C18/2008, C26/2010 a C20/2011 „Joint laboratory of ultrastructural morphology for Charles University, Czech Technical University and Czech University of Life Sciences, Prague.“ Principal co-ordinator doc. MVDr. L. Vajner, CSc., co-coordinators prof. RNDr. M. Jelínek, DrSc., a prof. Ing. J. Rozinek, CSc., co-workers prof. MUDr. R. Kodet, CSc., prof. MUDr. R. Druga, DrSc., doc. RNDr. E. Amler, CSc., prof. Ing. I. Langrová, CSc., 2008-2011.
GAUK 74108 „Is remodelling of the lung vessel walls in hypoxic pulmonary hypertension affected by stabilizing mast cells with disodium cromoglycate?“ Principal investigator MUDr. T. Novotný, co-investigator-tutor doc. MVDr. L. Vajner, CSc., co-investigators MUDr. J. Uhlík, Ph.D., MUDr. J. Malíková, R. Wasserbauer, K. Boháčková. 2008-2010.
GAUK 63008 „Observation of the intraocular concentration and toxicity of Hycamtin in the rabbit corpus vitreum after intravitreal and subconjunctival administrations“. Principal investigator MUDr. D. Darsová, co-investigator-tutor prof. MUDr. D. Dotřelová, CSc., co-investigators MUDr. P. Pochop, Ing. J. Kukačka, Ph.D., (since 2009 Ing. E. Klapková, Ph.D.) MUDr. J. Uhlík, Ph.D., MUDr. D. Kodetová, K. Boháčková, (since 2009 doc. MVDr. L. Vajner, CSc.). 2008-2010.
IGAMZ 9532-3
„Observation of dynamics of the cytostatics’ concentrations in the rabbit corpus vitreum after transcorneal and subconjunctival administrations.“ Principal investigator MUDr. P. Pochop, co-investigators MUDr. J. Mališ, MUDr. D. Darsová, MUDr. D. Kodetová, Ing. J. Kukačka, Ph.D., co-workers doc. MVDr. L. Vajner, CSc., MUDr. J. Uhlík, Ph.D., K. Boháčková. 2007-2009.

Two Programmes of development of MŠMT ČR, principal co-ordinators prof. MUDr. M. Vízek, CSc. and prof. MUDr. R. Kodet, CSc., co-coordinator doc. MVDr. L. Vajner, CSc., 2006.

FRVŠ 1031 Aa/2006 „Innovation of study rooms at Departments of Biology and Medical Genetics and Histology and Embryology.“ Principal co-ordinator doc. MVDr. L. Vajner, CSc., co-workers MUDr. J. Uhlík, doc. RNDr. J. Mareš, CSc., RNDr. E. Kočárek, Ph.D., 2006.
GA UK 55/2005 „Location of reactive oxygen species source in the lung tissue after transition from hypoxia to air breathing.“ Principal investigator MUDr. J. Tkaczyk, co-investigators prof. MUDr. M. Vízek, CSc., MUDr. B. Fišárková, MUDr. J. Uhlík, K. Boháčková, A. Trnková, 2005-2006.
GA UK 53/2005 „Morphology of the fetoplacental vascular bed influenced by chronic hypoxia.“ Principal investigator Mgr. A. Kleščová, co-investigators doc. MVDr. L. Vajner, CSc., K. Boháčková, MUDr. V. Jakoubek, prof. RNDr. V. Hampl, DrSc., H. Vulterinová, M. Malina, 2005-2006.
FRVŠ 1791 F3a/2004 „Introduction of the new study subject Embryology and Developmental Biology at the 2nd Faculty of Medicine, Charles University.“ Principal co-ordinator doc. RNDr. J. Mareš, CSc., co-workers doc. MVDr. L. Vajner, CSc., MUDr. J. Uhlík, 2004.
GA ČR 304/02/1348: „The role of mast cells in the pathogenesis of the pulmonary hypertension.“ Principal investigator prof. MUDr. J. Herget, DrSc., co-workers doc. MVDr. L. Vajner, CSc., MUDr. J. Uhlík, prof. MUDr. V. Konrádová, DrSc., 2002-2004.

GA UK 053/2002: "The role of collagenolytic metalloproteinases in the pathogenesis of the hypoxic pulmonary hypertension." Principal investigator RNDr. J. Novotná, CSc., co-investigators doc. MVDr. L. Vajner, CSc., MUDr. M. Vaňková, RNDr. R. Vytášek, MUDr. L. Bláhová, D. Hermochová, MUDr. V. Lachmanová, prof. MUDr. J. Herget, DrSc., Mgr. M. Kalinová, 2002-2003

GA UK 185/98: „Histochemical and imunohistochemical detection of changes in cells of the airway epithelium under experimental and pathologic conditions.“ Principal investigator MVDr. L. Vajner, CSc., co-investigators MUDr. J. Uhlík, R. Skřipský, M. Holemářová, M. Sokolová, 1998-2000.
GA UK 79/97: „Epithelium of bronchioles and its reaction to the administration of various substances.“ Principal investigator MUDr. J. Uhlík, co-investigators prof. MUDr. V. Konrádová, DrSc., a MVDr. L. Vajner, CSc., 1997-1999.
FRVŠ 1452/97: „Renovation of the microscopy hall for practical training students in histology and biology“, principal co-ordinator prof. MUDr. V. Konrádová, DrSc., co-coordinator prof. MUDr. P. Goetz, CSc., 1997
FRVŠ 464/96: „Extension of the practicals in teaching histology and embryology with regard to the cell and tissue ultrastructure.“ Principal co-ordinator prof. MUDr. V. Konrádová, DrSc., co-workers MUDr. J. Uhlík. a MVDr. L. Vajner, CSc., 1996
IGA MZ ČR 2859-3
: „The reaction of respiratory system organs to various diseases and diagnostic or therapeutic processes.“ Principal investigator prof. MUDr. V. Konrádová, DrSc., co-investigators MUDr. J. Uhlík. a MVDr. L. Vajner, CSc., 1995-1997
GAUK 234: „Effect of various drugs, therapeutic and diagnostic processes, injurants, and diseases to the ultrastructure of the airway epithelium.“ Principal investigator prof. MUDr. V. Konrádová, DrSc., co-imvestigators MUDr. J. Uhlík. a MVDr. L. Vajner, CSc., 1994-1996
Participation in Research projects:
No 111300003 - „Complex longitudinal clinical and genetic care of the prenatal and postnatal development of individuals and families with hazard of the medically and socially most serious diseases and abnormalities.“ Co-ordinators prof. MUDr. J. Vavřinec, CSc., a prof. MUDr. P. Goetz, CSc., 1999-2004
Part 8,5 - „Assessment of the risk level of therapy and refinement of diagnosis of the respiratory diseases“
No 111300002 - „Mechanisms of the tissue adaptation to the protracted hypoxia. Opportunities of the prediction and interference of pathogenic effects of hypoxia.“ Principal co-ordinator prof. MUDr. M. Vízek, CSc., 1999-2004